30-7 CAS Institute of Zoology applies genome editing to turn adult macaques into phenotypic models of Parkinsons’s disease
Parkinson’s disease (PD), with a prevalence of 2%–3% in people >65 years old, is the second-most common neurodegenerative disorder worldwide [1]. It is typically characterized by a cluster of specific motor symptoms, including bradykinesia, rigidity, postural instability and tremor. The existing classic monkey PD models, which are induced by the administration of neurotoxins such as […]