Month: April 2024

2024 UNESCO International Prize for Research in the Life Sciences goes to three scientists from China, Egypt and Greece

http://en.people.cn/n3/2024/0425/c90000-20161248.html https://www.unesco.org/en/prizes/equatorial-guinea Qiao Jie of China, Mohamed Ali Farag of Egypt, and Triantafyllos Stylianopoulos of Greece received the awards for outstanding contributions to improving the quality of human life through scientific research at a ceremony held in Addis Ababa on the sidelines of the 10th Africa Regional Forum on Sustainable Development. The prize is funded by Equatorial Guinea and is given annually to a maximum of three laureates. This year’s winners received a monetary award of 350,000 U.S. dollars, divided equally among them. It was handed over by Qu Xing, UNESCO deputy director-general. Qiao Jie is a specialist in reproductive medicine and won the prize for helping couples conceive healthy babies and improving reproductive health, especially for women. She studied the detailed genetic processes and developed innovative techniques for preimplantation genetic diagnosis, a procedure that can dramatically improve the success rate of in vitro fertilization (IVF) and help avoid the transmission of genetic diseases through IVF. Her most revolutionary contribution to improving women’s reproductive health has been her discovery of microbiomes that cure reproductive disorders among females. Farag is a specialist in metabolomics and one of the pioneers in this field in Africa. He has developed a metabolomic platform, which is the first of its kind in Africa. His discovery has enabled scientists to observe volatile compounds emitted by microbes for both medical and agricultural applications and has already aided in identifying novel biocontrol agents from soil bacteria that can boost plant growth. Stylianopoulos is spearheading research into cancer therapies. He won the prize for his research that leveraged the principles of biomechanics, blending physics and biology to improve the delivery and efficacy of cancer treatments for patients who face the grim prognosis of solid tumors.

Networked polymer gel electrolytes provide wearable batteries with high energy density

http://en.people.cn/n3/2024/0426/c90000-20162287.html https://www.nature.com/articles/s41586-024-07343-x Huishing Peng and colleagues from Fudan University in Shanghai have developed a strategy for designing channel structures in electrodes to incorporate polymer gel electrolytes and to form intimate and stable interfaces for high-performance wearable batteries. As a demonstration, multiple electrode fibres were rotated together to form aligned channels, while the surface of each electrode fibre was designed with networked channels. The monomer solution was effectively infiltrated first along the aligned channels and then into the networked channels. The monomers were then polymerized to produce a gel electrolyte and form intimate and stable interfaces with the electrodes. The team managed to fabricate fiber lithium-ion batteries with lengths of several kilometers and a high energy density that can effectively provide power for electrical devices like drones. They have established a pilot production line and achieved a production capacity of 300 watt-hours per hour, which is equivalent to the battery produced per hour capable of charging 20 mobile phones simultaneously. The concept shows promise for applications in firefighting and space exploration.

Advanced brain-machine interface (BMI) shown at 2024 Zhongguancun Forum in Beijing

https://english.news.cn/20240425/331ce62ba74e40908b35e26e89657fd5/c.html The NeuCyber Array BMI System, a brain-machine interface (BMI) system, was unveiled at the opening ceremony of the 2024 Zhongguancun Forum (ZGC Forum)  in Beijing. A video demonstration showed how  a monkey with its hands restrained and soft electrode filaments implanted in its brain, controlled an isolated robotic arm and grasped a strawberry by simply using its “thoughts.” The BMI is intended to serve as the “information highway” for the brain, facilitating communication with external devices and providing cutting-edge technologies in human-machine interaction and hybrid intelligence. It is composed of three major components — high-throughput flexible microelectrode array, a thousand-channel high-speed neural signal acquisition system, and a generative neural decoding algorithm based on a feedforward control mechanism. The electrodes determine the quality of the recorded brain signals and the accuracy of “brain control”. The BMI System makes use of a large number of extremely thin electrode contacts on a thin electrode thread to enhance signal capture ability.

CAS Shanxi Institute of Coal Chemistry develops multiphase rhodium catalyst for propylene hydroformylaion with ultra-high regioselectivity

https://www.nature.com/articles/s41586-024-07342-y https://www.cas.cn/syky/202404/t20240425_5012616.shtml Hydroformylation reaction catalyze the conversion of olefins to aldehydes under carbon monoxide and hydrogen atmosphere, an important way to utilize olefins in high value-added conversion. Globally, more than 10 million tons of olefins are converted at high value through this reaction pathway each year, and rhodium-catalyzed propylene hydroformylation accounts for more than 70% of all olefin hydroformylation capacity. The product of this process, n-butyraldehyde, is usually further converted to n-butanol and 2-ethylhexanol. Both are basic chemical raw materials for the production of bulk household products such as plasticizers, detergents, paints and pharmaceuticals. However, rhodium molecular catalysts are in the same phase as the raw materials and products, so catalyst separation and recycling after the reaction is accompanied by rhodium loss. A team of researchers from the CAS Shanxi Institute of Coal Chemistry, in cooperation with Sinosynthesis Oil Technology Co., has realized the production of n-butyraldehyde from the hydroformylation of propylene  with ultra-high regioselectivity by using a multiphase rhodium-molecular sieve-loaded catalyst system, with more than 99% regioselectivity. The catalytic performance results surpass all multiphase catalysts and almost all homogeneous catalysts reported so far.

CAS DICP develops high energy-density aqueous battery based on halogen multielectron transfer

https://english.cas.cn/newsroom/research_news/chem/202404/t20240423_660866.shtml https://www.nature.com/articles/s41560-024-01515-9 Traditional non-aqueous lithium-ion batteries have a high energy density, but their safety is compromised due to the flammable organic electrolytes they utilize. Aqueous batteries use water as the solvent for electrolytes, significantly enhancing battery safety. However, due to the limited solubility of the electrolyte and low battery voltage, aqueous batteries typically have lower energy density. This means that the amount of electricity stored per unit volume of aqueous battery is relatively low. A research team around LI Xianfeng and FU Qiang from CAS DICP developed a multielectron transfer cathode based on bromine and iodine, realizing a specific capacity of more than 840 Ah/L and achieving an energy density of up to 1200 Wh/L based on catholyte in full battery testing.  They consider there results as a new idea for the design of high-energy-density aqueous batteries, which may expand aqueous battery applications in the power battery field.

A windfarm at 5000 m altitude in Tibet

https://spc.jst.go.jp/news/240404/topic_4_04.html The first wind turbine was installed at the Core Satsakha 300MW Wind Power Plant in Tibet Autonomous Region, China. The wind farm has a maximum elevation of 5,193 meters, making it the largest wind farm under construction in the world in terms of elevation and stand-alone capacity. Located in the northern foothills of the Himalayas, it is only 140 km from the summit of Chomolungma (Mt. Everest). The total installed capacity is 300 megawatts (MW), of which 40 wind turbines with a stand-alone capacity of 5 MW will be installed, for a total of 200 MW. The single wind turbine will have a diameter of 183 meters, a blade length of 90.1 meters, a hub height of 105 meters, and a total weight of 483.9 tons. In normal operation, each revolution of a single blade can generate approximately 3 kW of electricity, or 5,000 kW per hour.

Dengue protection by changing the mosquito’s microbiome?

https://english.news.cn/20240419/c1645294c8f84729a9a1b0bd6a983f40/c.html https://www.science.org/content/article/bacteria-found-mosquito-guts-could-help-scientists-fight-dengue-zika Chinese scientists have developed a new strategy to prevent mosquito-borne diseases by changing insects’ gut microbes, as an alternative to experiments that see genetically-modified mosquitoes released in Florida. Mosquito-borne viruses, such as dengue and Zika, cause several potentially fatal human viral infections. Dengue viruses infect approximately 390 million each year globally. In China, an epidemic survey over the past decade documented frequent dengue outbreaks in Xishuangbanna and Lincang, both in southwest China’s Yunnan Province. But few have been reported in neighboring cities of Wenshan and Pu’er. The very different prevalence stimulated the curiosity of researchers from Tsinghua University and Yunnan Academy of Animal Science and Veterinary Sciences. Investigation on thousands of blood-sucking female mosquitoes revealed that mosquitoes from the two different habitats carry different symbiotic bacteria in their guts, the first tissue organ usually infected by viruses. Among the 55 strains isolated, a kind of bacterium called Rosenbergiella_YN46 was abundant in mosquito guts in Wenshan and Pu’er, but not in Xishuangbanna and Lincang. Then, the researchers colonized the strain in the intestines of two common disease-transmitting mosquitoes — Aedes albopictus and Aedes aegypti. Those mosquitoes did become less likely to be infected with dengue and Zika via blood bites, according to the study. Further analysis suggested that glucose oxidase secreted by the bacteria can convert glucose into gluconic acid and rapidly acidifies the intestines of blood-sucking mosquitoes, rapidly neutralising the mosquito-borne viruses in acid environment. As a consequence, the team tried to breed “good mosquitoes” that do not transmit viruses, by adding Rosenbergiella_YN46 bacteria to the water where mosquitoes eggs were laid and hatched. Encouragingly, the intestinal colonization proved a success at a site in Mengla County of Xishuangbanna and the colony persistently resided in the guts of Aedes mosquitoes. The researchers also proposed another potential intervention strategy — the use of plants. Mosquito’s gut microbes in the wild are either derived from microbes in breeding waters, or in the sap and nectar of plants. They collected a large number of plant samples in Wenshan, where the bacterium was isolated, in order to find plants that are enriched with this bacterium. Transplanting and cultivating this plant to the infected area might intervene in the ability of mosquitoes to carry and transmit the virus. If those plants were shrub or herbaceous plants, they could even be grown in backyards or residential compounds. This study has shown that the use of bacteria-colonized field mosquitoes could offer a feasible biocontrol strategy for reducing virus transmission and prevalence in nature.

New projects for submarine oil and gas production from the Bohai Sea field off Tianjin

http://j.people.com.cn/n3/2024/0411/c95952-20155847.html According to China National Offshore Oil Corporation (CNOOC) Tianjin Branch, construction of the Kengli 10-2 Oil Field Phase 1 and Kengli 10-1 Oil Field A54 Well Block Development Project began on April 10 at three construction sites in Tianjin and Qingdao City. As a result, the 100-million-ton large oil field “Kendri 10-2” has entered the development and construction phase. The oil field is located in the southern waters of the Bohai Sea, about 245 km from Tianjin, with an average water depth of about 15.7 meters. It is a large-scale petrographic oil and gas field discovered by China Sea Oil in the Laizhou Bay depression in 2021, with proven crude oil reserves of over 100 million tons. The project includes one new central platform and two unmanned wellhead platforms to be built in the “Kengri 10-2 oil field,” seven new subsea pipelines and four subsea cables to be laid, and will be an important project to achieve production capacity of 40 million tons of oil and gas and 3 million tons of heavy oil in the Bohai Sea oil field in 25 years The project will be an important project to achieve the production capacity of 40 million tons of oil and gas and 3 million tons of heavy oil in the Bohai Sea field in 25 years. The project’s CEPC platform module is currently the largest module in the Bohai field, with a floating weight of approximately 20,000 tons, which is close to the loading limit of a floating vessel.

China steps up independent production of carbon-14 and other isotopes

http://en.people.cn/n3/2024/0422/c90000-20159675.html According to the China National Nuclear Corporation, mass production of carbon-14 isotopes was achieved using a commercial nuclear reactor. Domestic production will break an import dependency on carbon-14 isotopes, and has significance for agriculture, chemistry, medicine and biography in the country, sectors that widely use the element in detecting helicobacter pylori and pharmacokinetics research. The carbon-14 isotope is produced by the Qinshan Nuclear Power Plant in East China’s Zhejiang Province, which is operated by a CNNC subsidiary. According to Fan Shen, a representative from the power plant, China’s annual demand for carbon-14 isotope used in helicobacter pylori detection alone is around 40 Curies, the total demand of scientific research is around 100 Curies. Qinshan Nuclear Power Plant’s production capacity can fully meet the current domestic demand, and the final product of the carbon-14 isotope will be supplied to the market by the end of 2024. China’s eight top departments on June 2021 issued the mid- and long-term development plan for medical isotopes from 2021 to 2035, which stated to build an independent and stable medical isotope supply system. In 2020, the Qinshan Nuclear Power Plant vowed to build China’s largest isotope production base by carrying out the development of related industries, according to CNNC. During the production of carbon-14, Qinshan Nuclear Power Plant also launched the mass production preparation for other isotopes including the lutecium-117 and yttrium-90, further upgrading China’s supply capability of medical isotopes.

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