Simple 45 min point-of-care test for COVID-19 without PCR: CAS Suzhou Institute of Biomedical Engineering and Technology
The hybrid-capture/FIA test is based on a monoclonal antibody S9.6 which recognizes DNA-RNA double-stranded hybrids from COVID-19 RNA coding for the conserved ORF 1ab, envelope protein and the nucleocapsid regions. S9.6-monoclonal-antibody-labelled europium-chelate-based fluorescent nanoparticles (FNPs) are then used to capture the hybridized double strands formed on a lateral flow strip. Hybridization time is 30 min, readout time for […]