CAS QIBEBT screens bakers’ yeast with better antifreeze performance using Raman-based FACS

https://www.cas.cn/syky/202410/t20241008_5034990.shtml

https://doi.org/10.1016/j.synbio.2024.09.004

The quality of baker’s yeast products is uneven, and there is a lack of fast, accurate and cost-effective methods to evaluate its quality of baker’s yeast. The Single Cell Research Center of CAS Qingdao Institute of Bioenergy and Processes and Tianjin Agricultural College have developed a new technology for quality inspection of baker’s yeast based on single-cell Raman spectroscopy.

The team incubated baker’s yeast cells with heavy water, and quantitatively analyzed the metabolic activity and viability of individual yeast cells based on the intensity of the heavy water peak in the Raman spectrum. In addition, the trehalose content in each yeast cells was measured through Raman spectra, as an indicator for antifreeze performance. High performing strains were screened out, subjected to genome sequencing and further cultured, resulting in improved strains for the yeast industry.

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Research Centers and universities in Qingdao (incomplete list)

R&D institutions

CAS Institute of Oceanology http://english.qdio.cas.cn/Internation/gjwyh/
CAS Center for Ocean Megascience http://www.coms.ac.cn/home/
CAS Qingdao Institute of Bioenergy and Environmental Technology QIBEBT http://www.qibebt.cas.cn
Shandong Energy Institute https://english.cas.cn/Special_Reports/Dual_Carbon_CAS_in_Action/Org/202204/t20220402_303477.shtml
Shandong University National Research Center for Colloidal Materials https://nccm.sdu.edu.cn/english/
Qingdao Haier Institute of Industrial Intelligence Co., Ltd. http://www.iecz.cn/content.action?formId=52&dataId=132&columnId=25&parentId=3
Hisense Medical https://medical.hisense.com/html/about_us/rd/
Vland Biotech http://www.vlandgroup.com/en/view/64.html

Universities in Qingdao

China University of Petroleum https://english.upc.edu.cn
Ocean University of China http://eweb.ouc.edu.cn
Shandong University of Science and Technology https://en.sdust.edu.cn
Qingdao University of Science and Technology https://en.qust.edu.cn
Qingdao University of Technology https://en.wikipedia.org/wiki/Qingdao_University_of_Technology
Qingdao Agricultural University https://en.qau.edu.cn

Photo: Haier Global Creative Research Center in Qingdao

Evonik and Vland Biotech form JV in Qingdao on animal gut health products

http://www.vlandbiochem.com/article-5545-10977.html

On March 14, 2024, Evonik Vland Biotech (Shandong) Co., Ltd. was put into operation in Qingdao, China. The joint venture of Evonik China Co., Ltd. and Shandong Vland Biotech Co., Ltd. aims to develop and expand gut health solutions products including probiotics for farm animals in China. Evonik holds the majority with a share of 55 %.

Head of Evonik’s life science division Nutrition & Care, the Animal Nutrition business line is Johann-Caspar Gammelin.

The joint venture is headquartered in Vland Biotech Innovation Park in Qingdao, China, and Vland’s production facilities in Binzhou, Shandong Province, China., will be utilized.

“Benefiting from the strong innovation capabilities, applied technology expertise and excellent reputation of the two parent companies, we will deliver innovative products and solutions to the market, and create more value for our customers,” says Dr. Wang Xu, general manager of Evonik Vland Biotech (Shandong) Co., Ltd.

Professor Juergen Popp, University of Jena, gives talk at QIBEBT on “Translational Biophotonics”

http://english.qibebt.cas.cn/ne/ns/202310/t20231027_397294.html

On Oct. 27, 2024, Prof. Juergen Popp Speaks, director of the Leibniz Institute of Photonic Technology and chair for Physical Chemistry at Friedrich-Schiller University, gave a talk at QIBEBT Distinguished Expert Forum and Visits Single-Cell Center on “Translational Biophotonics – Raman spectroscopy and AI a game changer !?” Popp elucidated the innovative technologies and potential applications of Raman spectroscopy in biophotonics, particularly its extensive use in clinical diagnostics. He emphasized the potential of multimodal methods combining Raman spectroscopy with other spectroscopic/optical technologies and how Raman can address today’s medical challenges, such as early cancer diagnosis and personalized treatments.

The visit was part of the Sino-German Scientific Partnership Program funded by the National Natural Science Foundation of China.

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