CAS Qingdao team develop single-cell precision diagnosis for Helicobacter pylori from gastric biopsy
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https://en.people.cn/n3/2025/0826/c90000-20357342.html
An ultra zero-carbon building, the headquarters of EV charging pile network operator TELD New Energy, was opened in Qingdao. It is quipped with cutting-edge high-tech solutions to achieve 100 percent green energy substitution.
http://english.cas.cn/newsroom/research_news/life/202508/t20250801_1048868.shtml
https://biotechnologyforbiofuels.biomedcentral.com/articles/10.1186/s13068-025-02677-8
A team at CAS Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) has developed a lipid-rich mutant strain of Saccharomyces cerevisiae for microbial production of palmitoleic acid— a rare omega-7 fatty acid with proven anti-inflammatory and metabolic benefits.
The team used a combined mutagenesis approach—employing zeocin, an antibiotic-based mutagen, and Atmospheric and Room Temperature Plasma (ARTP)—to create a diverse library of yeast mutants. They then deployed FlowRACS, a Raman flow cytometry system, to select live yeast cells with elevated lipid levels by analyzing their intrinsic single-cell Raman spectra, eliminating the need for chemical stains or genetic reporters.
This method identified the mutant strain MU2R48, which achieved a lipid content of 40.26%—a 30.85% increase over its parental strain SC018—while maintaining similar biomass production.
Photo: Raman flow cytometry efficiently identifies lipid-rich Saccharomyces cerevisiae mutants from a Zeocin–ARTP-induced library. (Image by QIBEBT)
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ICGC aims to provide an interdisciplinary academic exchange platform and academic community for scientific and technological innovation in the area of CO2 emission reduction and sustainable development. The conference will focus on carbon resources, carbon conversion technologies, carbon life cycle management, and breakthrough developments in green carbon science.
Qingdao Institute of Bioenergy and Bioprocess Technology, CAS/Shandong Energy Institute (QIBEBT/SEI) is a research institute that is active in science and technology developments of bioenergy, fossil energy, hydrogen energy, energy storage devices, and energy informatics, see http://english.qibebt.cas.cn
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