CAS TIB: improved Fusarium mycoprotein production through metabolic engineering

https://pubs.acs.org/doi/10.1021/acs.jafc.3c08509

A team of researchers from CAS Tianjin Institute of Industrial Biotechnology have applied a stepwise strategy to block the byproduct ethanol and the gluconeogenesis pathway in Fusarium venenatum, leading to improved mycoprotein production. Compared to the wild-type strain, the synthesis rate, carbon conversion ratio, and protein content of mycoprotein produced from the engineered strain were increased by 57% (0.212 vs 0.135 g/L·h), 62% (0.351 vs 0.217 g/g), and 57% (61.9 vs 39.4%), respectively, accompanied by significant reductions in CO2 emissions.

CAS TIB: improved Fusarium mycoprotein production through metabolic engineering
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