CAS Tianjin Institute of Industrial Biotechnology develops monoamine oxidase-based pathway to chiral amines

Researchers around Dunming ZHU from CAS TIB engineered a monoamine oxidase from Aspergillus niger and af cyclohexalamine oxidase from Brevibacterium through several rounds of iterative saturation mutagenesis to deracemize alicyclic secondary amines with high yields and to high enantiomeric purity. The project was done in collaboration with Peter Lau of McGill University, Montreal.

CAS news release, May 20, 2014

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