Team at CAS Tianjin Institute of Industrial Biotechnology solve mannanase structure, design heat-stable mutants

In cooperation with Taiwan-Bio, a Taiwanese Enzyme maker, the group of GUO Ruiiting solved the structure of Aspergillus niger ß-1,4-mannanase (ManBK) at 1,57 A resolution, and 23 mutants were designed, among which Y216W showed 18 % improved activity and higher temperature stability.

CAS news release, July 1, 2014

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