A neural probe probes simultaneously over 1000 neurons in vertebrate brains

http://en.people.cn/n3/2024/0626/c90000-20185859.html

https://www.nature.com/articles/s41593-024-01692-6

The research team led by Duan Xiaojie at Peking University has designed and produced a neural probe named Neuroscroll, which isolates single neuronal activities simultaneously from 1,024 densely spaced channels flexibly distributed across the probe. The probe length is tunable from 1 cm to 10 cm, covering the brain sizes ranging from those of rodent species to primates.

The team used the probes to achieve simultaneous monitoring of the activities of over 700 single neurons covering the entire depth of the macaque monkey brain. In addition, they have realized stable neural recording in the rat brain for up to two years, demonstrating the excellent biocompatibility and long-term recording stability of the probe. By implanting multiple probes, it is expected to further achieve neural recordings from up to tens of thousands of channels, which will bring transformative impacts to basic neuroscience and translational neuroscience research, such as brain-machine interfaces.

A neural probe probes simultaneously over 1000 neurons in vertebrate brains
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