CAS Guangzhou Institutes of Biomedicine and Health discovers that oncogene stops generation of iPS cells

In experiments with undifferentiated stem cells, the group of PEI Duanqing found that c-Jun, a well-known transcription factor and oncogen, resulted in the differentiation of embryonic stem cells but inhibited reprogramming of somatic cells cultured with the „Yamanaka factors“.

CAS news release, Sept. 28, 2015

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