CAS SIBS Shanghai cure genetic diseases in mouse germ cells using the CDRISPR-Cas9 system

Using a mouse strain suffering from cataracts, the group around Jinsong LI at SIBS Institute of Biochemistry and Cell Biology isolated spermatogonial stem cells from these mice and treated them with CRISPR-Cas9 technologies. After transplantation of the treated cells in the testes of recipient mice, 100 % completely healthy mice were obtained, suggesting a new procedure for gene therapy.

CAS news release, Dec. 9, 2014

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