The study was done by Professor ZHANG Xueli’s group at TIB. The pathway engineering involved is based on a synergistic effect of transhydrogenase and NAD kinase to increase NADPH supply and led to 10.8 g/L isobutanol production in 24 hrs with a yield of 0.62 mol/mol glucose
CAS news release, February 26, 2014
CAS Tianjin Institute of Industrial Biotechnology develops E. coli cell factory for i-butanol production