Team at CAS Institute of Biophysics finds mechanism of transient activation of autophagy crucial in iPS cell reprogramming

Transient activation of autophagy via Sox2-mediated suppression of mTOR is shown to be an important early step in reprogramming to pluripotency

Shuo WANG et al., Cell Stem Cell doi: 10.1016/j.stem.2013.10.005

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