Day: 5. November 2018

Antibiotic resistance genes in Chinese waters correlate with human activities

The groups of YANG Jun and ZHU Yongguan at the CAS Institute of Urban Environment have analyzed patterns of antibiotic resistance genes (ARG) in 42 natural lakes and reservoirs across China. Using high-throughput DNA sequencing, they detected 167 ARGs and 9 mobile genetic elements mostly coding for efflux transporters. Human activities strongly correlated with the normalized […]

A hyperthermophilic Ni-Fe hydrogenase drives the reduction of pyruvate to lactate in a cell-free system

The group of Yunhong SONG at CAS Institute of Industrial Biotechnology in Tianjin cloned a soluble enzyme I (SHI) from Pyrococcus furiosus and overexpressed it in Thermococcus kodakarensis. Purification was achieved in one step using a nickel-loaded column. The rSHI purified by this method was coupled with an FMN-containing diaphorase (DI) to form a new electron […]

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